Treatment of invasive ocular surface squamous neoplasia with proton beam therapy

Abstract

Figure 1 (a) Case 1 on presentation. (b) Case 1 at 9 months post treatment. (c) Haematoxylin and eosin (H&E)-stained section showing the in situ squamous carcinoma on the left (black arrow) and hyperplastic, non-neoplastic epithelium to the right (white arrow). Note the sharp demarcation between the neoplastic in situ disease and the non-neoplastic hyperplasic epithelium. (d) Higher power of plate C (H&E), showing the acantholytic, eosinophilic, atypical squamous cells of the in situ squamous carcinoma on the left. (e) Post treatment biopsy showing (H&E) conjunctiva with squamous metaplasia of the epithelium, without dysplasia. (f) Case 2 on presentation. (g) Case 2 at 8 months post treatment. (h) H&E-stained section showing the invasive squamous carcinoma (black arrow), undermining the overlying epithelium (white arrow). (i) Higher power of plate H (H&E), showing the invasive squamous carcinoma cells.

DOI: 10.1038/eye.2013.149

Cite this paper

@article{ElAssal2013TreatmentOI, title={Treatment of invasive ocular surface squamous neoplasia with proton beam therapy}, author={Karim El-Assal and Sachin M Salvi and Paul A Rundle and Hardeep Singh Mudhar and Ian George Rennie}, journal={Eye}, year={2013}, volume={27}, pages={1223-1224} }