Treatment of intraocular retinoblastoma with vincristine and carboplatin.

@article{RodriguezGalindo2003TreatmentOI,
  title={Treatment of intraocular retinoblastoma with vincristine and carboplatin.},
  author={Carlos Rodriguez-Galindo and Matthew W. Wilson and Barrett G. Haik and Thomas E. Merchant and Catherine A. Billups and Nirali Shah and Alvida M. Cain and James Douglas Langston and Mindy Lipson and Larry E. Kun and Charles B. Pratt},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2003},
  volume={21 10},
  pages={
          2019-25
        }
}
PURPOSE To evaluate the efficacy of chemoreduction using vincristine and carboplatin in preventing or delaying external-beam radiotherapy (EBRT) or enucleation in patients with intraocular retinoblastoma. PATIENTS AND METHODS Twenty-five patients (43 eyes) with newly diagnosed intraocular retinoblastoma received primary treatment with eight courses of vincristine and carboplatin. Focal treatments were delayed until documentation of disease progression. Outcome measures for each eye were… CONTINUE READING

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Systemic chemotherapy as a new conservative treatment for intraocular retinoblastoma

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