Treatment of infantile haemangioma with captopril.

  title={Treatment of infantile haemangioma with captopril.},
  author={Swee Thong Tan and Tinte Itinteang and Darren Day and Chris O'Donnell and Jon A Mathy and Phillip Leadbitter},
  journal={The British journal of dermatology},
  volume={167 3},
BACKGROUND Infantile haemangioma (IH) has recently been reported as an aberrant proliferation and differentiation of a primitive mesoderm-derived haemogenic endothelium regulated by the renin-angiotensin system (RAS), leading us to propose angiotensin converting enzyme (ACE) as a potential therapeutic target. OBJECTIVES To present initial results of our open-labelled observational clinical trial using captopril, an ACE inhibitor (ACEi), in the treatment of problematic proliferating IH… CONTINUE READING