Treatment of idiopathic rhinitis with kinetic oscillations – a multi-centre randomized controlled study

  title={Treatment of idiopathic rhinitis with kinetic oscillations – a multi-centre randomized controlled study},
  author={Anders Ehnhage and Pernilla Sahlstrand Johnsson and Cecilia Ahlstr{\"o}m-Emanuelsson and Morgan Andersson and Johan Knutsson and Jacob Lien and Tomas Norlander and Petter Olsson and Jan-Eric Friis-Liby and Mats Holmstr{\"o}m},
  journal={Acta Oto-Laryngologica},
  pages={852 - 859}
Abstract Conclusions: The potential effects of KOS are still uncertain regarding the most effective air pressure to be used as well as the physiological effects on the nasal mucosa. The results of the study do not support a convincing treatment effect by KOS on IR. Objectives: Idiopathic rhinitis (IR) is a common disorder, affecting ∼10–20% of the population. A new method for treating IR, Kinetic Oscillation Stimulation (KOS), has been reported to have beneficial effects on total vasomotor… 
Effectiveness of Kinetic Oscillation Stimulation Treatment in Patients with Non-Allergic Rhinitis Refractory to Conventional Medical Therapies
Kinetic Oscillation Stimulation treatment is a safe and mini-invasive procedure for the treatment of NAR symptoms, well accepted from patients and with a promising improvement of QoL, better than conventional medical therapies.
Kinetic oscillatory stimulation of nasal mucosa in non-allergic rhinitis: comparison of patient self-administration and caregiver administration regarding pain and treatment effect. A randomized clinical trial
Patient self-administration of the Kinetic Oscillatory Stimulation (KOS)-catheter was a fully acceptable alternative to insertion of the catheter by physician with helmet fixation, in patients with non-allergic rhinitis (NAR).
Rhinology Future Debates 2017 by EUFOREA: Novel treatments and surgical solutions in rhinology
  • W. Fokkens, B. Pugin, P. Hellings
  • Medicine
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • 2018
Debate topics presented here include: i) Real World Evidence data in AIT - What does it bring to us?, ii) Nasal turbinate as therapeutic target in patients with turbinate-induced nasal symptoms, and iii) Lessons from biologicals in asthma for ENT physicians.
Effects of intranasal kinetic oscillation stimulation on heart rate variability
Kinetic oscillation stimulation in the nasal cavity (KOS) has been shown to have positive symptomatic effects in subjects with non‐allergic rhinitis and in patients with migraine.
The Rhinology Future Debates is a unique clinician-orientated initiative organised by the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA), aiming at reducing the prevalence and burden of chronic respiratory diseases.
Vagus nerve stimulation modulates the cranial trigeminal autonomic reflex
Noninvasive vagal nerve stimulation (nVNS) may be an effective modulator of the trigeminal autonomic reflex in primary headache syndromes.


Kinetic oscillation stimulation as treatment of non-allergic rhinitis: an RCT study
Kinetic oscillation stimulation of nasal mucosa at low frequency seems to be a possibly effective and safe short-term treatment of non-allergic nasal stuffiness and no significant effect was observed for patients treated with placebo.
Mometasone furoate nasal spray in the treatment of perennial non-allergic rhinitis: a nordic, multicenter, randomized, double-blind, placebo-controlled study.
The therapeutic response showed greater improvement in total nasal score as recorded by the investigator in the groups treated with MFNS as compared to the placebo group, indicating that MFNS is a safe and effective treatment for patients with PNAR.
Powered-assisted partial turbinectomy versus mometasone furoate nasal spray for relief of nasal blockage in chronic or idiopathic rhinosinusitis
Power-assisted partial turbinectomy is a safe and reliable alternative for patients with nasal blockage if nasal corticosteroid spray therapy is not suitable and patients' self-reported symptoms decreased more for operated patients.
A multi-centre study on quality of life and absenteeism in patients with CRS referred for endoscopic surgery.
RARS, CRS+NP and CRS-NP significantly decrease HRQOL, and some statistically significant differences were found between the three rhinosinusitis subgroups.
Quality of life in non-allergic rhinitis depends on the predominant inflammatory cell type.
The first evidence that Quality of Life is impaired in NAR as well as in allergic rhinitis is provided, and there is a correlation with the cellular infiltrating type.
For treatment of patients with vasomotor rhinitis, intra-nasal BDA in a daily dose of 200 mug can be recommended when antihistamines, sympathomimetic drugs and sodium cromoglycate are not sufficiently effective.
A new therapy (MP29-02) is effective for the long-term treatment of chronic rhinitis.
Results confirm MP29-02's wide therapeutic spectrum and assert its consistent superiority over an intranasal corticosteroid in patients with chronic rhinitis.
Open-label evaluation of azelastine nasal spray in patients with seasonal allergic rhinitis and nonallergic vasomotor rhinitis*
Azelastine nasal spray was reported to control all Rhinitis symptoms, including nasal congestion, regardless of rhinitis diagnosis during the 2-week study period.
Psychometric and Clinimetric Validity of the 20-Item Sino-Nasal Outcome Test (Snot-20)
The psychometric and clinimetric validity of the 20-Item Sino-Nasal Outcome Test (SNOT-20), a disease-specific, health-related quality-of-life measure for rhinosinusitis, was analyzed.
Noninfectious, Nonallergic Rhinitis (NINAR): Considerations on Possible Mechanisms
Three potential functional abnormalities are discussed in this article: those associated with the aging process of the nasal mucosa, those resulting in various forms of nasal hyperreactivity, and those reflecting imbalanced neuronal control of end organs of the nose.