Treatment of human endometrial gland epithelial cells with chorionic gonadotropin/luteinizing hormone increases the expression of the cyclooxygenase-2 gene.

@article{Zhou1999TreatmentOH,
  title={Treatment of human endometrial gland epithelial cells with chorionic gonadotropin/luteinizing hormone increases the expression of the cyclooxygenase-2 gene.},
  author={Xi Ling Zhou and Zhemin Lei and Ch Venkateswara Rao},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1999},
  volume={84 9},
  pages={3364-77}
}
Endometrial glands contain higher levels of LH/hCG receptors than other cells in the human uterus. The present study investigated their functional importance. Northern and Western blotting and covalent receptor cross-linking demonstrated that human endometrial gland epithelial cells in culture contained multiple LH/hCG receptor transcripts and an 80-kDa receptor protein that can bind [125I]hCG in a hormone-specific manner. Culturing cells with highly purified hCG resulted in a time- and dose… CONTINUE READING

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