Treatment of hospital-acquired pneumonia with linezolid or vancomycin: a systematic review and meta-analysis
@article{Kalil2013TreatmentOH, title={Treatment of hospital-acquired pneumonia with linezolid or vancomycin: a systematic review and meta-analysis}, author={A. Kalil and M. Klompas and G. Haynatzki and M. Rupp}, journal={BMJ Open}, year={2013}, volume={3} }
Objective Hospital-acquired pneumonia remains the most lethal and expensive nosocomial infection worldwide. Optimal therapy remains controversial. We aimed to compare mortality and clinical response outcomes in patients treated with either linezolid or vancomycin. Design Systematic review and meta-analysis. Data sources PubMed, EMBASE, Cochrane Library, American College of Physicians Journal Club, Evidence-based Medicine BMJ and abstracts from infectious diseases and critical care meetings were… CONTINUE READING
Topics from this paper
Paper Mentions
61 Citations
Linezolid versus vancomycin for the treatment of suspected methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a systematic review employing meta-analysis
- Medicine
- European Journal of Clinical Pharmacology
- 2014
- 34
Efficacy and safety of linezolid versus vancomycin for methicillin-resistant Staphylococcus aureus (MRSA)-related pneumonia: updated systematic review and meta-analysis
- 2019
- Highly Influenced
- PDF
Linezolid versus vancomycin cost in the treatment of staphylococcal pneumonia.
- Medicine
- Medecine et maladies infectieuses
- 2019
Linezolid versus vancomycin for nosocomial pneumonia due to methicillin‐resistant Staphylococcus aureus in the elderly: A retrospective cohort analysis: Effectiveness of linezolid in the elderly
- Medicine
- The American journal of emergency medicine
- 2017
- 8
Proper use of antibiotics: situation of linezolid at the intensive care unit of the Tunisian Military Hospital
- Medicine
- The Pan African medical journal
- 2016
- 2
Risk of acute kidney injury in critically ill surgical patients with presumed pneumonia is not impacted by choice of methicillin-resistant staphylococcus aureus therapy
- Medicine
- International journal of critical illness and injury science
- 2018
- 1
References
SHOWING 1-10 OF 40 REFERENCES
Linezolid versus vancomycin for the treatment of gram-positive bacterial infections: meta-analysis of randomised controlled trials.
- Medicine
- International journal of antimicrobial agents
- 2010
- 82
Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study.
- Medicine
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- 2012
- 431
- PDF
Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia.
- Medicine
- Chest
- 2003
- 603
Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: A systematic review and meta-analysis*
- Medicine
- Critical care medicine
- 2010
- 103
- PDF
Linezolid vs glycopeptide antibiotics for the treatment of suspected methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a meta-analysis of randomized controlled trials.
- Medicine
- Chest
- 2011
- 103
- PDF
Efficacy and safety of linezolid compared with vancomycin in a randomized, double-blind study of febrile neutropenic patients with cancer.
- Medicine
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- 2006
- 148
- PDF
Linezolid (PNU-100766) versus vancomycin in the treatment of hospitalized patients with nosocomial pneumonia: a randomized, double-blind, multicenter study.
- Medicine
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- 2001
- 447
- PDF
Linezolid for the treatment of infections caused by Gram-positive pathogens in China.
- Medicine
- International journal of antimicrobial agents
- 2008
- 41
Linezolid versus vancomycin for treatment of resistant Gram-positive infections in children
- Medicine
- The Pediatric infectious disease journal
- 2003
- 146
Continuation of a randomized, double-blind, multicenter study of linezolid versus vancomycin in the treatment of patients with nosocomial pneumonia.
- Medicine
- Clinical therapeutics
- 2003
- 246
- PDF