Treatment of extensive-stage small cell lung carcinoma: current status and future prospects.

@article{Demedts2010TreatmentOE,
  title={Treatment of extensive-stage small cell lung carcinoma: current status and future prospects.},
  author={Ingel K. Demedts and Karim Y. Vermaelen and J-P van Meerbeeck},
  journal={The European respiratory journal},
  year={2010},
  volume={35 1},
  pages={202-15}
}
Small cell lung cancer (SCLC) is an aggressive lung tumour strongly associated with cigarette smoking, with patients often presenting with metastatic disease at the time of diagnosis. Although SCLC is very chemoradiosensitive and high response rates are obtained with treatment, relapse rates are high and the prognosis remains very poor. In limited-stage SCLC, the overall survival rate has been significantly improved by adding dose-hyperfractionated thoracic radiotherapy and prophylactic cranial… CONTINUE READING