Treatment of experimental murine cryptococcosis: a comparison of miconazole and amphotericin B.


Miconazole was compared with amphotericin B in the treatment of murine cryptococcosis. Both subcutaneous and intraperitoneal administration of miconazole produced serum levels higher than the minimum inhibitory concentration for the challenge strain. However, maximal tolerable doses of miconazole gave no increase in survival. When combined with amphotericin… (More)


8 Figures and Tables