Treatment of epilepsy in Rett syndrome.

@article{Huppke2007TreatmentOE,
  title={Treatment of epilepsy in Rett syndrome.},
  author={Peter Huppke and Karola Koehler and Knut Brockmann and Georg M. Stettner and Jutta Gaertner},
  journal={European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society},
  year={2007},
  volume={11 1},
  pages={10-6}
}
INTRODUCTION Epilepsy is very frequent in Rett syndrome (RTT) patients and often difficult to treat. Because most cases of RTT are caused by mutations in the MECP2 gene it is reasonable to assume that convulsions are based on common pathogenetic mechanisms and thus should have a similar response to antiepileptic drugs. PURPOSE To find the optimal treatment for epilepsy in RTT. METHODS We performed a retrospective study on 110 female patients with confirmed MECP2 mutations. RESULTS The… CONTINUE READING

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References

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Showing 1-10 of 29 references

Molecular diagnosis of rett syndrome

  • P Huppke, J. Gartner
  • J Child Neurol
  • 2005
Highly Influential
5 Excerpts

Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5/STK9) gene are associated with severe neurodevelopmental retardation

  • J Tao, H Van Esch, M Hagedorn-Greiwe
  • Am J Hum Genet
  • 2004

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