Treatment of early caries lesions using biomimetic self-assembling peptides – a clinical safety trial

@inproceedings{Brunton2013TreatmentOE,
  title={Treatment of early caries lesions using biomimetic self-assembling peptides – a clinical safety trial},
  author={P. A. Brunton and Robert Philip Wynn Davies and Julie L Burke and Alexandra Smith and Amalia Aggeli and Steven Joseph Brookes and Jennifer Kirkham},
  booktitle={BDJ},
  year={2013}
}
Objective We previously reported that a rationally designed biomimetic self-assembling peptide, P11−4, nucleated hydroxyapatite de novo and was apparently capable of in situ enamel regeneration following infiltration into caries-like lesions. Our present aim was to determine the safety and potential clinical efficacy of a single application of P11−4 on early enamel lesions.Materials and methods Fifteen healthy adults with Class V 'white spot' lesions received a single application of P11−4… CONTINUE READING

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