Treatment of diffuse systemic sclerosis with hyperimmune caprine serum (AIMSPRO): a phase II double-blind placebo-controlled trial

@inproceedings{Quillinan2014TreatmentOD,
  title={Treatment of diffuse systemic sclerosis with hyperimmune caprine serum (AIMSPRO): a phase II double-blind placebo-controlled trial},
  author={Niamh P Quillinan and David McIntosh and Jeffrey Vernes and S Haq and Christopher P. Denton},
  booktitle={Annals of the rheumatic diseases},
  year={2014}
}
OBJECTIVE The primary objective of the study was to explore safety and tolerability of hyperimmune caprine serum (AIMSPRO) in established diffuse cutaneous systemic sclerosis (SSc). Secondary objectives included assessment of potential efficacy and biological activity and exploration of candidate biomarkers. METHODS This was a double-blind parallel group randomised placebo-controlled clinical trial. After informed consent 20 patients with established diffuse cutaneous SSc of greater than 3… CONTINUE READING
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