Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine.

@article{Joffe2007TreatmentOD,
  title={Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine.},
  author={Hadine Joffe and Claudio N. Soares and Laura Fagioli Petrillo and Adele Casals Viguera and Brittny L Somley and Jennifer K. Koch and Lee S. Cohen},
  journal={The Journal of clinical psychiatry},
  year={2007},
  volume={68 6},
  pages={943-50}
}
BACKGROUND Postmenopausal women with depression frequently have co-occurring symptoms of hot flashes (vasomotor symptoms), sleep disturbance, anxiety, and pain. Treatment strategies that target all of these symptoms together have not been investigated to date. METHOD Study participants were postmenopausal women, 40 to 60 years old, with major depressive disorder (DSM-IV criteria) and vasomotor symptoms. The study design included a 2-week, single-blind placebo run-in phase followed by an 8… CONTINUE READING
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