Treatment of cutaneous viral warts in children: A review

@article{Soenjoyo2020TreatmentOC,
  title={Treatment of cutaneous viral warts in children: A review},
  author={Karina Ruth Soenjoyo and Brandon Wen Bing Chua and Lynette Wei Yi Wee and Mark Jean Aan Koh and Seng Bin Ang},
  journal={Dermatologic Therapy},
  year={2020},
  volume={33}
}
Viral warts or verruca are very common skin infections in children. Although benign, lesions can be extensive, painful, bleed, or lead to cosmetic disfigurement. Although spontaneous resolution can occur, parents often bring their children for treatment, especially when they are symptomatic. Many publications have assessed the efficacy and safety of treatment of warts in adults. However, treatment in children can be challenging due to their immune responses and lower threshold for pain. We… 

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SADBE topical immunotherapy is a safe, effective option for home therapy of warts in children and correlated with plantar distribution, wart duration under 2 years, and first-line therapy with SADBE.

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High quality evidence based studies are lacking in this discipline owing to confounding factors such as high rates of spontaneous resolution and a subpopulation of warts that seem recalcitrant to most treatments.

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CPS1 solution is a safe and promising treatment modality with a high clearance and high patient satisfaction rate for the management of cutaneous warts, particularly in children.

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Intralesional injection of Candida antigen is an effective and safe therapy for children with multiple and recalcitrant cutaneous warts and appears to be an effective alternative for the treatment of warts.

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Reviewed trials of local treatments for cutaneous warts were highly variable in methods and quality, and there was a paucity of evidence from randomised, placebo controlled trials on which to base the rational use of the treatments.

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It is found that pulsed dye laser therapy is safe, relatively effective, and worth considering as an additional therapeutic option for viral warts in children, although not as a first‐line therapy.

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The experience suggests intralesional candida antigen may represent a treatment option for warts and molluscum contagiosum that is safe and effective and may be overestimated, as many patients were also treated concurrently with liquid nitrogen or other therapies.

Efficacy of intralesional injection of mumps-measles-rubella vaccine in patients with wart

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