Treatment of complicated sarcoidosis with infliximab anti-tumor necrosis factor-alpha therapy.

@article{Yee2001TreatmentOC,
  title={Treatment of complicated sarcoidosis with infliximab anti-tumor necrosis factor-alpha therapy.},
  author={A M Yee and Mark Bennett Pochapin},
  journal={Annals of internal medicine},
  year={2001},
  volume={135 1},
  pages={27-31}
}
BACKGROUND Tumor necrosis factor-alpha (TNF-alpha) may have an important role in the clinical exacerbation of sarcoidosis. OBJECTIVE To treat sarcoidosis with infliximab, a chimeric human-murine anti-human TNF-alpha monoclonal antibody. DESIGN Case report. SETTING U.S. academic medical center. PATIENT A 72-year-old woman with sarcoidosis presenting with severe protein-losing enteropathy, hypoalbuminemia, and proximal myopathy who had not responded adequately to corticosteroid therapy… CONTINUE READING