Treatment of clostridium difficile infection

@article{Stroehlein2004TreatmentOC,
  title={Treatment of clostridium difficile infection},
  author={John R. Stroehlein},
  journal={Current Treatment Options in Gastroenterology},
  year={2004},
  volume={7},
  pages={235-239}
}
  • J. Stroehlein
  • Published 2004
  • Medicine, Biology
  • Current Treatment Options in Gastroenterology
Opinion statementWith the introduction of broad-spectrum antibiotics into clinical practice, Clostridium difficile infection has become the most common cause of infectious diarrhea in hospitalized patients. Although mild cases may resolve by discontinuing antibiotics, thus allowing re-establishment of colonic microflora, oral metronidazole or vancomycin is indicated if the process is more severe. Metronidazole may be given intravenously, with intracolonic therapeutic levels achieved by… 
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References

SHOWING 1-10 OF 30 REFERENCES

ORAL VANCOMYCIN FOR ANTIBIOTIC-ASSOCIATED PSEUDOMEMBRANOUS COLITIS

Treatment of recurrent Clostridium difficile colitis with vancomycin and Saccharomyces boulardii.

Saccharomyces boulardii, a nonpathogenic yeast, was found to be effective in preventing clindamycin cecitis recurrence in an animal model and may have a role in treating recurrent C. difficile diarrhea and colitis.

Intravenous immunoglobulin therapy for severe Clostridium difficile colitis

Passive immunotherapy with intravenous immunoglobulin may be a useful addition to antibiotic therapy for severe, refractory C difficile colitis.

BACTERIOTHERAPY FOR CHRONIC RELAPSING CLOSTRIDIUM DIFFICILE DIARRHOEA IN SIX PATIENTS

Recurrent Clostridium difficile diarrhea: characteristics of and risk factors for patients enrolled in a prospective, randomized, double-blinded trial.

Five factors were associated with a higher risk of RCDD: the number of previous CDD episodes, onset of the initial disease in the spring, exposure to additional antibiotics for treatment of other infections, infection with immunoblot type 1 or 2 strains of C. difficile, and female gender.

Human antibody response to Clostridium difficile toxin A in relation to clinical course of infection

Data suggest an association between a defective humoral response to toxin A and a more severe form of C. difficile infection and indicate that other host-related factors control the severity of CDAD and remain to be elucidated.