Treatment of chloroquine-resistant Plasmodium vivax with chloroquine and primaquine or halofantrine.

@article{Baird1995TreatmentOC,
  title={Treatment of chloroquine-resistant Plasmodium vivax with chloroquine and primaquine or halofantrine.},
  author={John Kevin Baird and H. Basri and Budi Subianto and David J. Fryauff and Peter D. McElroy and Budhi Leksana and Thomas L. Richie and Sofyan Masbar and Frank S Wignall and Stephen L Hoffman},
  journal={The Journal of infectious diseases},
  year={1995},
  volume={171 6},
  pages={1678-82}
}
Optimal therapy for infection by chloroquine-resistant Plasmodium vivax has not been established. From 1992 to 1994 during three separate studies, 147 Javanese residents of Irian Jaya infected by P. vivax were treated with either chloroquine (25 mg of base/kg during 3 days or 10 mg of base/kg in one dose) plus primaquine (10 mg/kg during 28 days or 2.5 mg/kg during 3 days) (n = 78), chloroquine plus placebo (n = 50), or halofantrine (24 mg base/kg in 12 h; n = 19). There was no difference in… CONTINUE READING

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