Treatment of childhood acute lymphoblastic leukemia.

  title={Treatment of childhood acute lymphoblastic leukemia.},
  author={Martin Stanulla and Martin Schrappe},
  journal={Seminars in hematology},
  volume={46 1},
Childhood acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood. Studies in ALL have been a model for clinical and basic research beyond pediatric hemato-oncology. As a result of sustained and well-organized research efforts since the early 1960s, childhood ALL now can be successfully treated in about 80% of patients by the application of intensive combination chemotherapy regimens, which in specific patient subgroups may need to be supplemented with radiation therapy… CONTINUE READING