Treatment of central sensitization in patients with 'unexplained' chronic pain: what options do we have?

  title={Treatment of central sensitization in patients with 'unexplained' chronic pain: what options do we have?},
  author={Jo Nijs and Mira Meeus and Jessica Van Oosterwijck and Nathalie Anne Roussel and Margot De Kooning and Kelly Ickmans and Milica Matic},
  journal={Expert opinion on pharmacotherapy},
  volume={12 7},
INTRODUCTION Central sensitization accounts for chronic 'unexplained' pain in a wide variety of disorders, including chronic whiplash-associated disorders, temporomandibular disorders, chronic low back pain, osteoarthritis, fibromyalgia, chronic fatigue syndrome and chronic tension-type headache among others. Given the increasing evidence supporting the clinical significance of central sensitization in those with unexplained chronic pain, the awareness is growing that central sensitization… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 6 times. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 34 extracted citations

Central Sensitization in Functional Chronic Pain Syndromes: Overview and Clinical Application.

Pain management nursing : official journal of the American Society of Pain Management Nurses • 2016
View 3 Excerpts


Publications referenced by this paper.
Showing 1-10 of 115 references

Applications of virtual reality for pain management in burn-injured patients.

Expert review of neurotherapeutics • 2008
View 4 Excerpts
Highly Influenced

Stimulation-induced analgesia: transcutaneous electrical nerve stimulation (TENS) and vibration

CJ Woolf, JW Thompson
Wall PD, Melzack R, editors, Textbook of pain. 3rd edition • 1995
View 13 Excerpts
Highly Influenced

Adverse effects of chronic opioid therapy for chronic musculoskeletal pain

Nature Reviews Rheumatology • 2010
View 3 Excerpts
Highly Influenced

Pharmacological treatment of fibromyalgia and other chronic musculoskeletal pain.

Best practice & research. Clinical rheumatology • 2007
View 4 Excerpts
Highly Influenced

Repetitive transcranial magnetic stimulation (rTMS) in experimentally induced and chronic neuropathic pain: a review.

The journal of pain : official journal of the American Pain Society • 2007
View 4 Excerpts
Highly Influenced

The use of repetitive transcranial magnetic stimulation (rTMS) in chronic neuropathic pain

Neurophysiologie Clinique/Clinical Neurophysiology • 2006
View 7 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…