Treatment of canine mast cell tumors with CCNU (lomustine).

@article{Rassnick1999TreatmentOC,
  title={Treatment of canine mast cell tumors with CCNU (lomustine).},
  author={Kenneth M. Rassnick and Antony S. Moore and Laurel E. Williams and Cheryl A London and Peter P. Kintzer and Silvia Engler and Susan M. Cotter},
  journal={Journal of veterinary internal medicine},
  year={1999},
  volume={13 6},
  pages={
          601-5
        }
}
The efficacy and toxicity of CCNU (1-[2-chloroethyl]3-cyclohexyl-1-nitrosourea) were evaluated in 23 dogs with measurable mast cell tumors (MCT). Twenty-two dogs had cutaneous MCT and 1 dog had an intranasal MCT Nineteen (83%) dogs had biopsy of their original mass performed and 4 (17%) had aspiration cytology of masses. Of the 19 tumors histologically graded, 1 (5%) neoplasm was classified as grade I, 10 (53%) were grade II, and the remaining 8 (42%) were grade III. Dogs were treated with CCNU… CONTINUE READING
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