Treatment of canine-generalized demodicosis: a blind, randomized clinical trial comparing the efficacy of Advocate(Bayer Animal Health) with ivermectin.

@article{Paterson2009TreatmentOC,
  title={Treatment of canine-generalized demodicosis: a blind, randomized clinical trial comparing the efficacy of Advocate(Bayer Animal Health) with ivermectin.},
  author={Tara E Paterson and Richard E. W. Halliwell and Paul J. Fields and Marta Lanza Louw and Jakobus P Louw and Geoff S Ball and Rhonda D Pinckney and John S McKibben},
  journal={Veterinary dermatology},
  year={2009},
  volume={20 5-6},
  pages={447-55}
}
Advocate (moxidectin 2.5% + imidacloprid 10%) is a multiparasiticidal agent authorized for treating canine demodicosis in many countries. This blind, randomized clinical trial assessed the efficacy of Advocate at varying treatment intervals and compared it with that of oral ivermectin. Fifty dogs with generalized demodicosis were randomly assigned to one of four treatment groups: oral ivermectin (500 microg/kg once daily), Advocate applied at the authorized dose monthly (ADV1), every 2 weeks… CONTINUE READING

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