Treatment of cancers involving the liver and porta hepatis with external beam irradiation and intraarterial hepatic fluorodeoxyuridine.

@article{Lawrence1991TreatmentOC,
  title={Treatment of cancers involving the liver and porta hepatis with external beam irradiation and intraarterial hepatic fluorodeoxyuridine.},
  author={Theodore Steven Lawrence and L M Dworzanin and S C Walker-Andrews and James C. Andrews and Randall K. Ten Haken and I S Wollner and Allen S. Lichter and William D. Ensminger},
  journal={International journal of radiation oncology, biology, physics},
  year={1991},
  volume={20 3},
  pages={555-61}
}
A Phase I/II clinical trial was designed for patients with malignancies of the liver and porta hepatis. This protocol employed three concepts: a) boost treatment to gross tumor within the liver for selected patients, determined by the dose-volume histogram (DVH) of the normal liver that would be irradiated by boost treatment; b) concurrent use of intraarterial hepatic 5-fluorodeoxyuridine (FdUrd) as a radiosensitizer; and c) hyperfractionation (1.5 Gy fractions given bid greater than 4 hr apart… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Similar Papers

Loading similar papers…