Treatment of bipolar disorder.

  title={Treatment of bipolar disorder.},
  author={John R. Geddes and David J. Miklowitz},
  volume={381 9878},
We review recent developments in the acute and long-term treatment of bipolar disorder and identify promising future routes to therapeutic innovation. Overall, advances in drug treatment remain quite modest. Antipsychotic drugs are effective in the acute treatment of mania; their efficacy in the treatment of depression is variable with the clearest evidence for quetiapine. Despite their widespread use, considerable uncertainty and controversy remains about the use of antidepressant drugs in the… CONTINUE READING
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