Treatment of bioprosthetic heart valve tissue with long chain alcohol solution to lower calcification potential.

@article{Pathak2004TreatmentOB,
  title={Treatment of bioprosthetic heart valve tissue with long chain alcohol solution to lower calcification potential.},
  author={Chandrashekar P Pathak and Alan K Adams and Tom Simpson and Richard E. Phillips and Mark A. Moore},
  journal={Journal of biomedical materials research. Part A},
  year={2004},
  volume={69 1},
  pages={140-4}
}
The use of glutaraldehyde-treated biological tissue in heart valve substitutes is an important option in the treatment of heart valve disease. These devices have limited durability, in part, because of tissue calcification and subsequent tearing of the valve leaflets. Components thought to induce calcification include lipids, cell remnants, and residual glutaraldehyde. We hypothesized that treatment of glutaraldehyde-treated bioprosthetic heart valve material using a short and long chain… CONTINUE READING