• Medicine
• Published in Dermatologic therapy 2011
• DOI:10.1111/j.1529-8019.2011.01421.x

Treatment of alopecia areata: "What is new on the horizon?".

@article{Hordinsky2011TreatmentOA,
  title={Treatment of alopecia areata: "What is new on the horizon?".},
  author={Maria Hordinsky},
  journal={Dermatologic therapy},
  year={2011},
  volume={24 3},
  pages={
          364-8
        }
}

• Maria Hordinsky

New drug treatment opportunities based on the results of a genome-wide association study, which implicate T cell and natural killer (NK)-cell activation pathways, are leading to new approaches in future clinical trials of alopecia areata. Special attention is being given to the UL 16-binding protein (ULBP3) gene cluster on chromosome 6q25, as these genes make the NKG2D-activating ligand or signal that can trigger the NKG2D receptor, initiating an autoimmune response. A greater expression of… CONTINUE READING

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