Treatment of adult and pediatric high-grade gliomas with Withaferin A: antitumor mechanisms and future perspectives

Abstract

Resistance mechanisms employed by high-grade gliomas allow them to successfully evade current standard treatment of chemotherapy and radiation treatment. Withaferin A (WA), utilized in Ayurvedic medicine for centuries, is attracting attention for its antitumor capabilities. Here we review pertinent literature on WA as a high-grade glioma treatment, and… (More)
DOI: 10.1007/s11418-016-1020-2

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Cite this paper

@article{Marlow2016TreatmentOA, title={Treatment of adult and pediatric high-grade gliomas with Withaferin A: antitumor mechanisms and future perspectives}, author={Megan M. Marlow and Sumedh Subodh Shah and Eduardo A. V{\'e}liz and Michael E. Ivan and Regina M Graham}, journal={Journal of Natural Medicines}, year={2016}, volume={71}, pages={16-26} }