Treatment of adult acute lymphoblastic leukemia with allogeneic bone marrow transplantation. Multivariate analysis of factors affecting acute graft-versus-host disease, relapse, and relapse-free survival.

@article{Doney1991TreatmentOA,
  title={Treatment of adult acute lymphoblastic leukemia with allogeneic bone marrow transplantation. Multivariate analysis of factors affecting acute graft-versus-host disease, relapse, and relapse-free survival.},
  author={Kristine C Doney and Lloyd D Fisher and Frederick R Appelbaum and C. Dean Buckner and Rainer F Storb and Jack W. Singer and Alexander Fefer and Claudio Anasetti and Peter G Beatty and William Ira Bensinger},
  journal={Bone marrow transplantation},
  year={1991},
  volume={7 6},
  pages={453-9}
}
Between February 1972 and December 1987, 192 adults (greater than or equal to 18 years old) with acute lymphoblastic leukemia were transplanted using genotypically HLA-identical marrow donors. Median patient age was 23 years. Eighty-nine patients were in marrow remission and 103 were in relapse. Conditioning regimens included chemotherapy alone (three patients) or in combination with 9.2-17.5 Gy total body irradiation (189 patients). Graft-versus-host disease (GVHD) prophylaxis consisted of… CONTINUE READING

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