Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis.

@article{Schulman2014TreatmentOA,
  title={Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis.},
  author={Sam Schulman and Ajay Kakkar and Samuel Z. Goldhaber and Sebastian W Schellong and Henry Ture Eriksson and Patrick Mismetti and Anita Vedel Christiansen and Jeffrey Friedman and Florence Le Maulf and Nuala Peter and Clive Kearon},
  journal={Circulation},
  year={2014},
  volume={129 7},
  pages={764-72}
}
BACKGROUND Dabigatran and warfarin have been compared for the treatment of acute venous thromboembolism (VTE) in a previous trial. We undertook this study to extend those findings. METHODS AND RESULTS In a randomized, double-blind, double-dummy trial of 2589 patients with acute VTE treated with low-molecular-weight or unfractionated heparin for 5 to 11 days, we compared dabigatran 150 mg twice daily with warfarin. The primary outcome, recurrent symptomatic, objectively confirmed VTE and… CONTINUE READING
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