Treatment of acute metabolic acidosis: a pathophysiologic approach

@article{Kraut2012TreatmentOA,
  title={Treatment of acute metabolic acidosis: a pathophysiologic approach},
  author={Jeffrey A Kraut and Nicolaos E Madias},
  journal={Nature Reviews Nephrology},
  year={2012},
  volume={8},
  pages={589-601}
}
  • J. Kraut, N. Madias
  • Published 4 September 2012
  • Medicine, Biology
  • Nature Reviews Nephrology
Acute metabolic acidosis is associated with increased morbidity and mortality because of its depressive effects on cardiovascular function, facilitation of cardiac arrhythmias, stimulation of inflammation, suppression of the immune response, and other adverse effects. Appropriate evaluation of acute metabolic acidosis includes assessment of acid–base parameters, including pH, partial pressure of CO2 and HCO3− concentration in arterial blood in stable patients, and also in central venous blood… 
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