Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen.

@article{Pohjolainen2000TreatmentOA,
  title={Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen.},
  author={Timo H Pohjolainen and Antti Jekunen and Lassi Autio and Heikki Vuorela},
  journal={Spine},
  year={2000},
  volume={25 12},
  pages={
          1579-85
        }
}
STUDY DESIGN A prospective, randomized double-blind comparative trial. OBJECTIVES To evaluate the efficacy and tolerability of nimesulide, a cyclooxygenase (COX)-2-selective anti-inflammatory agent versus ibuprofen in patients with acute lumbosacral back pain. SUMMARY OF BACKGROUND DATA Nonsteroidal anti-inflammatory drugs (NSAIDs) have been more effective than placebo in patients with uncomplicated acute low back pain in previous randomized controlled trials. The efficacy and tolerability… CONTINUE READING
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