Treatment of acute disseminated encephalomyelitis with intravenous immunoglobulin.

  title={Treatment of acute disseminated encephalomyelitis with intravenous immunoglobulin.},
  author={Demetrios J. Sahlas and Steven Paul Miller and Mark Guerin and M. Veilleux and Gordon Francis},
  volume={54 6},
Acute disseminated encephalomyelitis (ADEM) is a presumed immune-mediated, demyelinating disease of the CNS for which the standard treatment is high-dose steroids. We describe two patients with ADEM in whom treatment with IV methylprednisolone coincided with deterioration in their clinical status. They were subsequently treated with IV immunoglobulin and exhibited dramatic clinical improvement, with return to their previous level of functioning. 

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