Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a nonpeptide platelet glycoprotein IIb/IIIa inhibitor: report of four cases.

@article{Junghans2001TreatmentOA,
  title={Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a nonpeptide platelet glycoprotein IIb/IIIa inhibitor: report of four cases.},
  author={Ulrich Junghans and R{\"u}diger J. Seitz and H J Wittsack and Albrecht Aulich and Mario Siebler},
  journal={Radiology},
  year={2001},
  volume={221 3},
  pages={
          795-801
        }
}
In four patients with acute basilar artery thrombosis, complete arterial recanalization and good neurologic outcome were achieved with a treatment combining alteplase with tirofiban. In no cases were cerebral or extracerebral hemorrhagic complications observed. Combined fibrinolytic agents and glycoprotein IIb/IIIa inhibitors may have high potential in the treatment of acute cerebrovascular thrombosis. 
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