Treatment of active and postactive ileal and colonic Crohn's disease with oral pH-modified-release budesonide. German Budesonide Study Group.

@article{Caesar1997TreatmentOA,
  title={Treatment of active and postactive ileal and colonic Crohn's disease with oral pH-modified-release budesonide. German Budesonide Study Group.},
  author={Inka Caesar and Volker Gro\ss and Marguerite Roth and Tilo Andus and Carsten L Schmidt and Richard Raedsch and Audrey Weber and Michael Gierend and Klaus Ewe and Juergen Schoelmerich},
  journal={Hepato-gastroenterology},
  year={1997},
  volume={44 14},
  pages={445-51}
}
BACKGROUND/AIMS Budesonide is a glucocorticoid with a high topical anti-inflammatory but low systemic activity due to its rapid hepatic inactivation. The aim of this open, multicenter study was to investigate efficacy and safety of oral pH-modified-release budesonide in patients with active Crohn's disease of the ileum and colon and in maintaining budesonide-induced remission in postactive Crohn's disease. MATERIALS AND METHODS 81 patients (intention-to-treat) received 3 x 3 mg budesonide/day… CONTINUE READING

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