Treatment of acne with tea tree oil (melaleuca) products: a review of efficacy, tolerability and potential modes of action.

  title={Treatment of acne with tea tree oil (melaleuca) products: a review of efficacy, tolerability and potential modes of action.},
  author={Katherine A. Hammer},
  journal={International journal of antimicrobial agents},
  volume={45 2},
  • K. Hammer
  • Published 1 February 2015
  • Medicine
  • International journal of antimicrobial agents
Role of tea tree oil in treatment of acne
The efficacy, safety, and tolerability of TTO for the treatment of acne is reviewed and it is indicated that the TTO is an appropriate option for treating mild-to-moderate acne.
A comparative study on the effectiveness of herbal extracts vs 2.5% benzoyl peroxide in the treatment of mild to moderate acne vulgaris
Although there is a standard guideline for the treatment of acne, it is still a common skin disease, and suboptimal medication adherence is a major reason for treatment failure. Herbal extracts are
The Role of Herbal Medicine in the Treatment of Acne Vulgaris: A Systematic Review of Clinical Trials
Evidence is provided that medicinal plants and phytochemicals are promising treatments for mild to moderate acne vulgaris, however, more quality of evidence and standardized methodologies are needed to support their effectiveness and safety claims.
Tea tree oil gel for mild to moderate acne; a 12 week uncontrolled, open‐label phase II pilot study
The efficacy, tolerability and acceptability of a tea tree oil gel (200 mg/g) and face wash (7 mg/g) were evaluated for the treatment of mild to moderate facial acne.
Azelaic acid and Melaleuca alternifolia essential oil co-loaded vesicular carrier for combinational therapy of acne.
The findings suggests that the combination of AzA and tea tree oil with ethosome hydrogel composite could be a potential treatment used for acne management.
Tea tree oil: a promising essential oil
Abstract The use of essential oils (EOs) in the perfumery, agriculture, food industry and cosmetics is quite common owing to their aromatic properties. Tea tree oil is an EO with immense potential
Tea Tree Oil and Its Use in Aromatherapy
In this review historical, and morphological information about M. alternifolia plant, chemical properties related to TTO and the mechanism of antimicrobial, antiviral and antifungal actions will be explained, relying extensively on existing literature.
Safety and efficacy of combined essential oils for the skin barrier properties: In vitro, ex vivo and clinical studies
To evaluate the safety and the synergistic effects of tea tree, lavender, eucalyptus and tangerine essential oils in combination on the skin using in vitro, ex vivo and clinical studies.
Therapeutic Efficacy of Sesquiterpene Farnesol in Treatment of Cutibacterium acnes-Induced Dermal Disorders
The results suggest that the topical application of a gel containing farnesol is a promising alternative remedy for acne vulgaris.


Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties
This review summarizes recent developments in understanding of the antimicrobial and anti-inflammatory activities of the tea tree oil and its components, as well as clinical efficacy.
Tea tree oil cream appears to reduce the symptomatology of tinea pedis as effectively as tolnaftate 1% but is no more effective than placebo in achieving a mycological cure.
A comparative study of tea‐tree oil versus benzoylperoxide in the treatment of acne
5% tea‐tree oil and 5% benzoyl peroxide had a significant effect in ameliorating the patients' acne by reducing the number of inflamed and non‐inflamed lesions (open and closed comedones), although the onset of action in the case of tea‐ tree oil was slower.
A review of the toxicity of Melaleuca alternifolia (tea tree) oil.
Tea tree oil reduces histamine‐induced skin inflammation
Summary Background  Tea tree oil is the essential oil steam‐distilled from Melaleuca alternifolia , an Australian native plant. In recent years it has become increasingly popular as an antimicrobial
Susceptibility of Propionibacterium acnes to the essential oil of Melaleuca alternifolia
The susceptibility of 32 strains of Propionibacterium acnes to the essential oil of Melaleuca alternifolia, tea tree oil, was examined using a broth dilution method. The minimum bactericidal
Botanical and Phytochemical Therapy of Acne: A Systematic Review
Clinical studies that have investigated the use of botanical agents in the treatment of acne vulgaris reported favorable results, and several showed equal or superior treatment to standard therapies, although further research is warranted.
A Clinical Study on the Effect of a Cream Containing Ramulus Mori Extract and Tea Tree Oil on Acne Vulgaris and Aerobic Skin Flora
Sebum secretion rates in acne patients were higher than those in control, but not statistically significant, and the total number of aerobic bacteria in acne Patients was higher than that in control.
Comparison of Clinical and Histological Effects between Lactobacillus-Fermented Chamaecyparis obtusa and Tea Tree Oil for the Treatment of Acne: An Eight-Week Double-Blind Randomized Controlled Split-Face Study
LFCO treatment was rapid and effective for treating acne lesions compared to TTO, and Histopathological findings correlated well with the clinical acne grade and treatment response.
The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study.
Topical 5% tea tree oil is an effective treatment for mild to moderate acne vulgaris and side-effects with both groups were relatively similar and tolerable.