Treatment of Steroid and Cyclosporine-Resistant Idiopathic Nephrotic Syndrome in Children

@inproceedings{Nikibakhsh2011TreatmentOS,
  title={Treatment of Steroid and Cyclosporine-Resistant Idiopathic Nephrotic Syndrome in Children},
  author={Ahmad Ali Nikibakhsh and Hashem Mahmoodzadeh and Mohammad Karamyyar and S. Hejazi and Mehran Noroozi and Ali Agayar Macooie},
  booktitle={International journal of nephrology},
  year={2011}
}
Steroid-resistant nephrotic syndrome (SRNS) in children carries a significant risk of progression to end-stage renal failure (ESRF). We report a two-step protocol adapted in children with SRNS. Thirty-seven SRNS were treated with cyclosporine A (CyA) in association with prednisolone (alternate day) for 6 months (first-step treatment). Twelve patients (32.4%) went into complete remission, and 2 (5.4%) got partial remission. The other 23 cases who were steroid and CyA resistant entered a second… CONTINUE READING
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