Treatment of Marburg and Ebola hemorrhagic fevers: a strategy for testing new drugs and vaccines under outbreak conditions.

@article{Bausch2008TreatmentOM,
  title={Treatment of Marburg and Ebola hemorrhagic fevers: a strategy for testing new drugs and vaccines under outbreak conditions.},
  author={Daniel G. Bausch and Armand G. Sprecher and Benjamin Jeffs and Paul Boumandouki},
  journal={Antiviral research},
  year={2008},
  volume={78 1},
  pages={150-61}
}
The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease--approaching 90% in many outbreaks. In recent years, laboratory research on the filoviruses has produced treatments and vaccines that are effective in laboratory animals and that could potentially drastically reduce case-fatality rates and curtail outbreaks in humans. However, there are significant challenges in clinical testing of… CONTINUE READING
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