Treatment of Marburg Variant Multiple Sclerosis with Mitoxantrone

  title={Treatment of Marburg Variant Multiple Sclerosis with Mitoxantrone},
  author={Douglas R. Jeffery and David S. Lefkowitz and J. Crittenden},
  journal={Journal of Neuroimaging},
Marburg variant multiple sclerosis (MS) is a severe, sometimes monophasic, form of MS leading to advanced disability or death within a period of weeks to months. No consistently successful treatment for Marburg variant MS has been described. The case reported here is that of a 34‐year‐old woman with Marburg variant MS whose magnetic resonance imaging scan showed extensive brainstem, periventricular white matter, subcortical, and cortical involvement, giving the appearance of an “MS cerebritis… 

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