Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo.
- John Carey
- Otolaryngologic clinics of North America
41 patients suffering from severe Menière's disease who were previously unsuccessfully treated with either a saccotomy or intensive medical therapy, were treated with intratympanically applied gentamicin sulphate. 16 mg was given daily and the average total dose was 88.8 mg. In 66% of the patients the vertiginous attacks ceased after treatment and in 17% they were greatly improved. The hearing was preserved in 66% of the patients and actually improved in 17%. In 49% of the patients the sensation of aural pressure was abolished and 34% were relieved of their tinnitus.