Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells: A Randomized Controlled Trial.

@article{Vega2015TreatmentOK,
  title={Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells: A Randomized Controlled Trial.},
  author={Aurelio Vega and Miguel Angel Mart{\'i}n-Ferrero and Francisco Del Canto and Mercedes Alberca and Ver{\'o}nica Garc{\'i}a and Anna Munar and Llu{\'i}s Orozco and Robert R. Soler and Juan Jos{\'e} Fuertes and Marina Huguet and Ana S{\'a}nchez and Javier Garc{\'i}a-Sancho},
  journal={Transplantation},
  year={2015},
  volume={99 8},
  pages={
          1681-90
        }
}
BACKGROUND Osteoarthritis is the most prevalent joint disease and a common cause of joint pain, functional loss, and disability. Conventional treatments demonstrate only modest clinical benefits without lesion reversal. Autologous mesenchymal stromal cell (MSC) treatments have shown feasibility, safety, and strong indications for clinical efficacy. We performed a randomized, active control trial to assess the feasibility and safety of treating osteoarthritis with allogeneic MSCs, and we obtain… CONTINUE READING

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