Treatment of Helicobacter pylori infection in rhesus monkeys using a novel antiadhesion compound.

@article{Mysore1999TreatmentOH,
  title={Treatment of Helicobacter pylori infection in rhesus monkeys using a novel antiadhesion compound.},
  author={Jagannatha V. Mysore and T Wigginton and Prof. Dr. med. C. Simon and David Zopf and Lillie M. Heman-Ackah and Andr{\'e} DuBois},
  journal={Gastroenterology},
  year={1999},
  volume={117 6},
  pages={1316-25}
}
BACKGROUND & AIMS Helicobacter pylori can be eradicated by administration of antimicrobials, but resistant strains have emerged, and there is a need for novel therapeutic approaches against this infection. This study aimed to determine the safety and efficacy of 3'-sialyllactose sodium salt (3'SL), an oligosaccharide that occurs naturally in human and bovine milk and that can inhibit the adhesion of H. pylori to human epithelial cells in vitro. METHODS Twelve H. pylori-positive rhesus monkeys… CONTINUE READING

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