Treatment of Chronic Posterior Laryngitis With Esomeprazole

@article{Vaezi2006TreatmentOC,
  title={Treatment of Chronic Posterior Laryngitis With Esomeprazole},
  author={Michael Fredrick Vaezi and Joel E Richter and Charles Richard Stasney and Joseph R. Spiegel and Ralph A. Iannuzzi and Joseph A. Crawley and Clara Hwang and Mark Sostek and Reza Shaker},
  journal={The Laryngoscope},
  year={2006},
  volume={116}
}
Objective: To evaluate the efficacy of acid‐suppressive therapy with the proton pump inhibitor esomeprazole on the signs and symptoms of chronic posterior laryngitis (CPL) in patients with suspected reflux laryngitis. 

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References

SHOWING 1-10 OF 25 REFERENCES

Empiric Esomeprazole in the Treatment of Laryngopharyngeal Reflux

Objective Objectives were to determine the efficacy of empiric treatment with esomeprazole for patients diagnosed with laryngopharyngeal reflux and to determine a treatment paradigm for this patient

Evaluation of Omeprazole in the Treatment of Reflux Laryngitis: A Prospective, Placebo‐Controlled, Randomized, Double‐Blind Study

The objective of this study was to determine the efficacy of omeprazole in treating proven reflux laryngitis.

Observations on the pathogenesis of chronic Non‐Specific pharyngitis and laryngitis

Repeated analysis of cinephotographic and cinefluorographic studies, correlated with clinical observations, have provided insight into the physiopathology of many cases of chronic non‐specific

The Reliability of the Assessment of Endoscopic Laryngeal Findings Associated With Laryngopharyngeal Reflux Disease

The reliability of the assessment of laryngoscopic findings potentially associated with lARYngopharyngeal reflux disease (LPRD) is investigated.

Intrapharyngeal Distribution of Gastric Acid Refluxate

The aims of the study were to determine intrapharyngeal distribution of gastric acid refluxate and to determine whether this distribution can better differentiate patients from control subjects compared with data obtained from a single hypopharyngeals site.

Laryngopharyngeal Reflux: Prospective Cohort Study Evaluating Optimal Dose of Proton‐Pump Inhibitor Therapy and Pretherapy Predictors of Response

An open label prospective cohort study is performed to evaluate whether twice‐daily PPI is more effective than once‐daily (QD) PPI for the treatment of LPR.

Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial

Empirical treatment with lansoprazole is efficacious in relieving symptoms of laryngeal symptoms compared to placebo and can be considered as a first-line option in managing patients with idiopathic chronic laryngitis.

Proton Pump Inhibitor Therapy for Chronic Laryngo-Pharyngitis: A Randomized Placebo-Control Trial

  • D. StewardK. Wilson J. Welge
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2004

Effect of Pantoprazole on the Course of Reflux-Associated Laryngitis: a Placebo-Controlled Double-Blind Crossover Study

The self-limited nature of reflux-associated laryngitis in non-smokers is largely underestimated and pantoprazole may be helpful especially in relieving acute symptoms, but the advantage of long-term treatment over placebo has been greatly overestimated.

Isolated head and neck symptoms due to hiatus hernia.

Symptoms of foreign-body sensation in the throat, hoarseness, neck pain, otalgia, or intractable cough were found in 22 patients with hiatus hernia and reflux. Of these, 21 had hoarseness or