Treatment of Chronic Pain With Various Buprenorphine Formulations: A Systematic Review of Clinical Studies

@article{Aiyer2018TreatmentOC,
  title={Treatment of Chronic Pain With Various Buprenorphine Formulations: A Systematic Review of Clinical Studies},
  author={Rohit Aiyer and Amitabh Gulati and S. Gungor and Anuj Bhatia and Neel Mehta},
  journal={Anesthesia \& Analgesia},
  year={2018},
  volume={127},
  pages={529–538}
}
Clinical studies demonstrate that buprenorphine is a pharmacologic agent that can be used for the treatment of various types of painful conditions. This study investigated the efficacy of 5 different types of buprenorphine formulations in the chronic pain population. The literature was reviewed on PubMed/MEDLINE, EMBASE, Cochrane Database, clinicaltrials.gov, and PROSPERO that dated from inception until June 30, 2017. Using the population, intervention, comparator, and outcomes method, 25… 

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