Treatment of Cells with Detergent Activates Caspases and Induces Apoptotic Cell Death

Abstract

Due to their amphiphilic properties, detergents readily disrupt cellular membranes and cause rapid cytolysis. In this study we demonstrate that treatment of cells with sublytic concentrations of detergents such as Triton X-100, Nonidet P-40, n-octylglucoside and the bile salt sodium deoxycholate induce typical signs of apoptosis including DNA fragmentation… (More)
DOI: 10.1007/s00232001066

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