Treatment of Bolivian hemorrhagic fever with intravenous ribavirin.

  title={Treatment of Bolivian hemorrhagic fever with intravenous ribavirin.},
  author={Paul E Kilgore and Thomas Ksiazek and Pierre E. Rollin and James N. Mills and M. Rodriguez Villagr{\'a} and Manuel Montenegro and Marina Costales and La. Paredes and Clarence J. Peters},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={24 4},
Bolivian hemorrhagic fever (BHF) is a potentially severe febrile illness caused by Machupo virus (family Arenaviridae). Initial symptoms include headache, fever, arthralgia, and myalgia. In the later stages of this illness, patients may develop hemorrhagic manifestations including subconjunctival hemorrhage, epistaxis, hematemesis, melena, and hematuria, as well as neurological signs including tremor, seizures, and coma. During the BHF epidemics of the 1960s, convalescent-phase immune plasma… CONTINUE READING


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