Treatment of Amatoxin Poisoning: 20-Year Retrospective Analysis
@article{Enjalbert2002TreatmentOA, title={Treatment of Amatoxin Poisoning: 20-Year Retrospective Analysis}, author={Françoise Enjalbert and Sylvie Rapior and Janine Nouguier-Soul{\'e} and S Guillon and No{\"e}l Amouroux and Claudine Cabot}, journal={Journal of Toxicology: Clinical Toxicology}, year={2002}, volume={40}, pages={715 - 757} }
Background: Amatoxin poisoning is a medical emergency characterized by a long incubation time lag, gastrointestinal and hepatotoxic phases, coma, and death. This mushroom intoxication is ascribed to 35 amatoxin-containing species belonging to three genera: Amanita, Galerina, and Lepiota. The major amatoxins, the α-, β-, and γ-amanitins, are bicyclic octapeptide derivatives that damage the liver and kidney via irreversible binding to RNA polymerase II. Methods: The mycology and clinical syndrome…
335 Citations
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