Treatment of Alzheimer's disease: current status and new perspectives.

  title={Treatment of Alzheimer's disease: current status and new perspectives.},
  author={Elio Scarpini and Philip Scheltens and Howard Feldman},
  journal={The Lancet. Neurology},
  volume={2 9},
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the most prevalent cause of dementia with ageing. Pharmacological treatment of AD is based on the use of acetylcholinesterase inhibitors, which have beneficial effects on cognitive, functional, and behavioural symptoms of the disease, but their role in AD pathogenesis is unknown. Other pharmacological therapies are becoming available--including the recently approved drug memantine, an NMDA channel blocker indicated for… CONTINUE READING