Treatment of Acute Psychosis Without Neuroleptics: Two-Year Outcomes From the Soteria Project

@article{Bola2003TreatmentOA,
  title={Treatment of Acute Psychosis Without Neuroleptics: Two-Year Outcomes From the Soteria Project},
  author={John R. Bola and Loren R. Mosher},
  journal={The Journal of Nervous and Mental Disease},
  year={2003},
  volume={191},
  pages={219-229}
}
  • J. Bola, L. Mosher
  • Published 1 April 2003
  • Psychology, Medicine
  • The Journal of Nervous and Mental Disease
The Soteria project (1971–1983) compared residential treatment in the community and minimal use of antipsychotic medication with “usual” hospital treatment for patients with early episode schizophrenia spectrum psychosis. Newly diagnosed DSM-II schizophrenia subjects were assigned consecutively (1971 to 1976, N = 79) or randomly (1976 to 1979, N = 100) to the hospital or Soteria and followed for 2 years. Admission diagnoses were subsequently converted to DSM-IV schizophrenia and… 

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TLDR
It is suggested that the Soteria paradigm yields equal, and in certain specific areas, better results in the treatment of people diagnosed with first- or second-episode schizophrenia spectrum disorders when compared with conventional, medication-based approaches.

Antipsychotic medication for early episode schizophrenia.

TLDR
The preliminary pattern of evidence suggests that people with early episode schizophrenia treated with typical antipsychotic medications are less likely to leave the study early than those treated with placebo, and there is very little useable data in the few studies meeting inclusion criteria.

Psychosocial Acute Treatment in Early-Episode Schizophrenia Disorders

TLDR
Evidence on the treatment of early episode schizophrenia spectrum disorders that contradicts the American Psychiatric Association’s generic recommendation of antipsychotic medication treatment for at least a year is reviewed.

Is non-pharmacological treatment an option for certain schizophrenia patients?

TLDR
Whether all schizophrenic people should be treated with antipsychotics for the same good prognosis is answered, and solutions for better outcomes in a greater number of patients using alternative treatment are provided.

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TLDR
The majority of the longitudinal studies of schizophrenia report that up to 30-50% of patients present with a favorable course, Interestingly, this moderately positive outcome is de-emphasized in the literature, which most times focuses on the bleaker outcome of the rest of the patients.
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