Treatment of 171 patients with pulmonary tuberculosis resistant to isoniazid and rifampin.

@article{Goble1993TreatmentO1,
  title={Treatment of 171 patients with pulmonary tuberculosis resistant to isoniazid and rifampin.},
  author={Marian Goble and Michael D. Iseman and Louis A Madsen and Dennis Waite and Lynn Ackerson and Charles Robert Horsburgh},
  journal={The New England journal of medicine},
  year={1993},
  volume={328 8},
  pages={527-32}
}
BACKGROUND AND METHODS The frequency of infection with multidrug-resistant Mycobacterium tuberculosis is increasing. We reviewed the clinical courses of 171 patients with pulmonary disease due to M. tuberculosis resistant to rifampin and isoniazid who were referred to our hospital between 1973 and 1983. The patients' records were analyzed retrospectively. Their regimens were selected individually and preferably included three medications that they had not been given previously and to which the… CONTINUE READING

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