Treatment-mediated changes in human immunodeficiency virus (HIV) type 1 RNA and CD4 cell counts as predictors of weight growth failure, cognitive decline, and survival in HIV-infected children.

@article{Lindsey2000TreatmentmediatedCI,
  title={Treatment-mediated changes in human immunodeficiency virus (HIV) type 1 RNA and CD4 cell counts as predictors of weight growth failure, cognitive decline, and survival in HIV-infected children.},
  author={Jane C. Lindsey and Michael R. Hughes and Ross E. McKinney and Mary Kathryn Cowles and Janet A Englund and Carol J. Baker and Sandra K. Burchett and Mark W. Kline and Andrea Kov{\'a}cs and John M. Moye},
  journal={The Journal of infectious diseases},
  year={2000},
  volume={182 5},
  pages={1385-93}
}
This meta-analysis of 5 large studies of the Pediatric AIDS Clinical Trials Group was undertaken to evaluate the predictive value of antiretroviral treatment-mediated changes in 3 markers of human immunodeficiency virus (HIV) type 1 disease progression-HIV-1 RNA level, CD4 cell count, and CD4 percentage-for weight growth failure, cognitive decline, and survival in HIV-infected children. Proportional hazards models were used to assess the prognostic value of the markers at baseline and after 24… CONTINUE READING

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