Treatment implications of the emerging molecular classification system for melanoma.

@article{Romano2011TreatmentIO,
  title={Treatment implications of the emerging molecular classification system for melanoma.},
  author={Emanuela Romano and Gary K. Schwartz and Paul B Chapman and Jedd D. Wolchock and Richard D. Carvajal},
  journal={The Lancet. Oncology},
  year={2011},
  volume={12 9},
  pages={
          913-22
        }
}
Melanoma is an aggressive disease with few standard treatment options. The conventional classification system for this disease is based on histological growth patterns, with division into four subtypes: superficial spreading, lentigo maligna, nodular, and acral lentiginous. Major limitations of this classification system are absence of prognostic importance and little correlation with treatment outcomes. Recent preclinical and clinical findings support the notion that melanoma is not one… CONTINUE READING
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