Treatment for lupus nephritis: a revisit.

@article{Lai2005TreatmentFL,
  title={Treatment for lupus nephritis: a revisit.},
  author={Kar Neng Lai and Sydney C. W. Tang and Chi Chiu Mok},
  journal={Nephrology},
  year={2005},
  volume={10 2},
  pages={
          180-8
        }
}
The optimal treatment of severe lupus nephritis remains unclear. Regimens consisting of steroid and cyclophosphamide (CYC) appear to be most effective. Infection and gonadal toxicity is a major concern of CYC use in patients of reproductive age. In addition, failure to respond or refractory to CYC treatment may lead to the development of end-stage renal disease. Mycophenolate mofetil (MMF) is a new immunosuppressive agent that selectively inhibits activated lymphocytes and renal mesangial cells… CONTINUE READING
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